The museum was created on March 7, 1980 by the Order of the university administration with the participation of the Vice-Rector of Science Eshanov I.E. and members of Kholjuraev Kh.Kh and Madaminov A.A.

A significant contribution to the creation of the museum was made by the former university rector Academician Yusufbekov H.Yu., Vice-Rector for Academic Affairs Rizoev AB, Director of the National Exhibition of Economic Achievements of Tajikistan RakhmatzodaU.K., Chairman of the Union Committee Makhmadkarimov A.M., artist Vataga S.P. and other famous figures of the republic.

March 4, 1982 the opening of the museum. On the eve of the 70th anniversary of the university with the support of the rector B. S. Tagaev in 2001, the museum was equipped with new stands and materials.

In 2009, on the occasion of the 80th anniversary of TAU named after Sh. Shotemur and the visit of rectors of leading agricultural universities of the CIS, the museum was renovated, supplemented with new posters, updated stands of all faculties, exhibition equipment, photos of all university achievements supported by the Rector of TAU, academician Tagaeva D.S.

During the reconstruction and repair of the museum at that time, the pro-rectors took an active part; A. Salimov; Kadyrov, T.A., Hasanov, N.R., Urokov.Y, deans of faculties; Makhmaderov, U. M., Karimov, M., Kadyrov, K., Samandarov, I., Habibov A., Boyeva, N., teachers Kosymov R., Mirzoyev B., Amirshoev F., Nurmatov K., Bobokhonova Z., Saidaliev M., Technical staff; Jabborov M., Yusupov I., Saidov Sh., Khakimov M., Sharipov R., Rajabov N., Jobirov M., Safaraliev R. and others.